Brizola Toscan R, Lesiński W, Stomma P, Subramanian B, Łabaj PP and Rudnicki WR (2025) Antimicrobial resistance in diverse urban microbiomes: uncovering patterns and predictive markers. Front. Genet. 16:1460508. doi: 10.3389/fgene.2025.1460508 Antimicrobial resistance (AMR) is a growing global health concern, driven by urbanization and anthropogenic activities. This study investigated AMR distribution and dynamics across microbiomes from six U.S. cities, focusing on resistomes, viromes, and mobile genetic elements (MGEs). Using metagenomic…
Tag: random forest
New paper in Frontiers in Genetics!
Polewko-Klim A, Zhu S, Wu W, Xie Y, Cai N, Zhang K, Zhu Z, Qing T, Yuan Z, Xu K, Zhang T, Lu M, Ye W, Chen X, Suo C and Rudnicki WR. Identification of Candidate Therapeutic Genes for More Precise Treatment of Esophageal Squamous Cell Carcinoma and Adenocarcinoma. Frontiers in Genetics 2022 13:844542. doi: 10.3389/fgene.2022.844542 The standard therapy administered to patients with advanced esophageal cancer remains uniform, despite its…
New paper in Biology Direct!
W. Lesiński, K. Mnich, A. Kitlas Golińska, W.R. Rudnicki. Integration of human cell lines gene expression and chemical properties of drugs for Drug Induced Liver Injury prediction. Biology Direct 16:2 (2021). DOI: 0.1186/s13062-020-00286-z (100 pkt. MNiSzW) Motivation Drug-induced liver injury (DILI) is one of the primary problems in drug development. Early prediction of DILI can bring a significant reduction in the cost of clinical trials. In this work we examined…
Our new paper is out!
A. Polewko-Klim, W. Lesiński, A. Kitlas Golińska, K. Mnich, M. Siwek, W. R. Rudnicki. Sensitivity analysis based on the Random Forest machine learning algorithm identifies candidate genes for regulation of innate and adaptive immune response of chicken. Poultry Science 99 (2020), 12, 6341-6354. DOI: 10.1016/j.psj.2020.08.059 (140 pkt. MNiSzW) Spożywanie zdrowej żywności m.in. produktów drobiarskich ma wielkie znaczenie dla zdrowia ludzi. Zwalczanie chorób drobiu to jeden z największych problemów jego producentów….